ea0016p428 | Neuroendocrinology | ECE2008
Berardelli Rita
, Margarito Enrica
, Ghiggia Federica
, Picu Andreea
, Bonelli Lorenza
, Balbo Marcella
, Giordano Roberta
, Bo Mario
, Arvat Emanuela
Central serotoninergic activity (CSA) is known to influence the hypothalamuspituitaryadrenal (HPA) axis, and a CSA loss seems to play a role in human brain aging and in etiology of functional hypercortisolism and depression, whose incidence increase with advancing age. Citalopram (CT), a SSRI, has been considered a good tool to evaluate CSA in humans. Aim of this study was to evaluate the neuroendocrine response to CT in healthy adult subjects during lifespan. We e...